In Acevedo v. State, 255 S.W.3d 162, 167 (Tex. App.-San Antonio 2008, pet. ref'd), the record showed the expert, a psychiatrist and pharmacist, possessed no information whatsoever about the particular facts of the case; the expert had no information about the defendant's individual characteristics, previous drug use, drug tolerance, how much of the drug was ingested, when the drug was ingested, and what other substances were ingested. Id. Under these circumstances, the Court concluded the expert's testimony was speculative, and therefore, unreliable and irrelevant. Id. at 169-70.